http://www.EvidenceBased.net This feed will automatically provide you with notifications of new updates on the EvidenceBased.net site en-au http://www.evidencebased.net/img/cube3.gif http://www.evidencebased.net/ EvidenceBased.net Dr. Gordon S. Doig Gordon S. Doig Thu, 12 Jul 2007 04:23:51 GMT FeedEdit http://icu-10.med.usyd.edu.au/ebdm/journal/therapy86.shtml A failure to report outcomes on 37% of enrolled and randomised patients is unacceptable. Elizabeth A Sweetman Fri, 27 Mar 2009 03:06:43 GMT Journal Club http://icu-10.med.usyd.edu.au/ebdm/journal/therapy87.shtml Perhaps a reduction in 6 hours of ventilation... but what happens when you consider the outcomes of the patients who develop severe diarrhea??? EA Sweetman Fri, 27 Mar 2009 03:04:25 GMT Journal Club http://icu-10.med.usyd.edu.au/ebdm/journal/therapy83.shtml Not really a trial of Early vs Late EN... its actually Early vs Late full goals. Its also pseudo-randomised.... Elizabeth Sweetman Fri, 30 Jan 2009 01:28:22 GMT Journal Club http://icu-10.med.usyd.edu.au/ebdm/journal/therapy84.shtml 28% lost to follow-up, not reported by group. Why??? Elizabeth Sweetman Fri, 30 Jan 2009 01:26:53 GMT Journal Club http://icu-10.med.usyd.edu.au/ebdm/journal/meta33.shtml A reveiw of the recommendation for early EN. Because its trendy ;) Pip Heighes Mon, 24 Nov 2008 02:27:28 GMT Journal Club http://icu-10.med.usyd.edu.au/ebdm/journal/meta34.shtml Interesting. Is acute illness like critical illness??? Pip Heighes Mon, 24 Nov 2008 02:26:04 GMT Journal Club http://icu-10.med.usyd.edu.au/ebdm/journal/meta32.shtml A reduction in mortality in a group of elective surgery patients at very low risk of mortality. Interesting... Pip Heighes Tue, 18 Nov 2008 03:31:47 GMT Journal Club http://icu-10.med.usyd.edu.au/ebdm/journal/meta31.shtml Inconclusive review of current trials. Pip Heighes Tue, 18 Nov 2008 03:30:28 GMT Journal Club http://icu-10.med.usyd.edu.au/ebdm/journal/therapy81.shtml Interesting results. Dose too low? Wrong patients? Just plain doesn't work? Unfortunately because this was a level II trial, the results won't change practice. Amit Kansal Tue, 18 Nov 2008 03:26:49 GMT Journal Club http://icu-10.med.usyd.edu.au/ebdm/journal/therapy82.shtml Very well conducted trial... may help with difficult to vent ARDS patients. Amit Kansal Wed, 10 Sep 2008 22:24:14 GMT Journal Club http://icu-10.med.usyd.edu.au/ebdm/journal/therapy46.shtml Our review has been updated as a result of controversy surrounding 25 missing patients who may have been randomised into the trial. If they were randomised into the trial, they should have contributed towards the ITT analysis. Gordon S Doig Fri, 05 Sep 2008 01:03:24 GMT Journal Club http://icu-10.med.usyd.edu.au/ebdm/journal/therapy79.shtml Very interesting paper. Not quite so 'convincing' when I re-did the analysis under more conservative assumptions. Gordon S Doig Thu, 31 Jan 2008 22:01:28 GMT Journal Club http://icu-10.med.usyd.edu.au/ebdm/journal/therapy75.shtml With 21 post-hoc subgroup analyses, you would expect we could identify a group were steroids work?? Greg Comadira Tue, 22 Jan 2008 22:04:11 GMT Journal Club http://icu-10.med.usyd.edu.au/ebdm/journal/harm6.shtml Is there a major flaw in this paper? Gordon Doig Thu, 08 Nov 2007 00:45:28 GMT Journal Club http://icu-10.med.usyd.edu.au/ebdm/journal/therapy72.shtml Although this trial was conducted at 95% power, we can only rule out a 20% difference in mortality between groups. A 5%, 10 or 15% difference may still be present. All would be clinically important!! John Field Thu, 08 Nov 2007 00:45:23 GMT Journal Club http://icu-10.med.usyd.edu.au/ebdm/journal/GradeA33.shtml Supports the use of aPC for the treatment of severe sepsis in adults who would have qualified for inclusion in PROWESS. Gordon S Doig Thu, 20 Sep 2007 00:23:39 GMT Evidence-based Recommendation http://icu-10.med.usyd.edu.au/ebdm/journal/therapy73.shtml Review of the ADDRESS trial. Gordon S Doig Thu, 20 Sep 2007 00:22:35 GMT Journal Club http://icu-10.med.usyd.edu.au/ebdm/journal/therapy70.shtml Very intersting pooled analysis of three recent RCTs. Gordon Doig Thu, 12 Jul 2007 04:22:28 GMT Journal Club http://icu-10.med.usyd.edu.au/ebdm/journal/meta28.shtml oral application of antiseptics significantly reduced the incidence of ventilator associated pneumonia Gordon S Doig Thu, 05 Jul 2007 02:58:39 GMT Journal Club http://icu-10.med.usyd.edu.au/ebdm/journal/therapy69.shtml ITT analysis conducted under conservative assumptions does NOT show reduction in reintubation rates. Gordon S Doig Wed, 06 Jun 2007 23:30:50 GMT Journal Club http://icu-10.med.usyd.edu.au/ebdm/journal/therapy67.shtml Review of a landmark trial for the treatment of organophosphate poisoning. Very important in many countries. Stuart Green Wed, 23 May 2007 02:03:08 GMT Journal Club http://icu-10.med.usyd.edu.au/ebdm/journal/therapy68.shtml Review of the latest levosimendan trial. Jon Field Wed, 23 May 2007 02:01:52 GMT Journal Club http://icu-10.med.usyd.edu.au/ebdm/journal/therapy66.shtml Review of the latest Glutamine RCT in critically ill patients. Ken Havill Tue, 22 May 2007 05:28:28 GMT Journal Club http://www.evidencebased.net/files 282 page book that provides in-depth critical appraisals of all ICU-based feeding trials and presents the results of a bi-national guideline development process. Gordon Doig and Fiona Simpson Wed, 31 Jan 2007 21:17:27 GMT E-B guidelines http://icu-10.med.usyd.edu.au/ebdm/journal/therapy63.shtml Review of the recent selenium in sepsis trial published in CCM Gordon S. Doig Thu, 01 Feb 2007 02:27:49 GMT Journal Club http://icu-10.med.usyd.edu.au/ebdm/journal/therapy64.shtml Review of the recent Phase II (physiological surrogate outcome) trial published in CCM. Gordon S. Doig Thu, 01 Feb 2007 02:27:57 GMT Journal Club